Publications

  1. George GK, Kuttan G (2016) Inhibition of pulmonary metastasis by Emilia sonchifolia (L.) DC: An in vivo experimental study. Phytomedicine : international journal of phytotherapy and phytopharmacology 23:123-130
  2. Gilcy GK, Kuttan G (2016) Evaluation of Antiangiogenic Efficacy of Emilia sonchifolia (L.) DC on Tumor-Specific Neovessel Formation by Regulating MMPs, VEGF, and Proinflammatory Cytokines. Integr Cancer Ther 4:1534735416630807
  3. Murali VP, Kuttan G (2016) CurculigoorchioidesGaertn Effectively Ameliorates the Uro- and Nephrotoxicities Induced by Cyclophosphamide Administration in Experimental Animals. Integr Cancer Ther 15:205-215
  4. Murali VP, Kuttan G (2016) Curculigoside augments cell-mediated immune responses in metastatic tumor-bearing animals. ImmunopharmacolImmunotoxicol 38:264-269
  5. Firdous AP, Kuttan G, Kuttan R (2015) Anti-inflammatory potential of carotenoid meso-zeaxanthin and its mode of action. Pharmaceutical biology 53:961-967
  6. Gilcy GK, Kuttan G (2015) Immune response modulatory effect of Emilia sonchifolia (L.) DC: an in vivo experimental study. J Basic ClinPhysiolPharmacol 26:613-622
  7. Murali VP, Kuttan G (2015) Enhancement of cancer chemotherapeutic efficacy of cyclophosphamide by CurculigoorchioidesGaertn and its ameliorative effects on cyclophosphamide-induced oxidative stress. Integr Cancer Ther 14:172-183
  8. Remya V, Kuttan G (2015) Homeopathic remedies with antineoplastic properties have immunomodulatory effects in experimental animals. Homeopathy 104:211-219
  9. Siveen KS, Kuttan G (2013) Inhibition of B16F-10 melanoma-induced lung metastasis in C57BL/6 mice by Aervalanata via induction of apoptosis. Integr Cancer Ther 12:81-92
  10. Gulati A, Sunila ES, Kuttan G (2012) IRL-1620, an endothelin-B receptor agonist, enhanced radiation induced reduction in tumor volume in Dalton's Lymphoma Ascites tumor model. Arzneimittelforschung 62:14-17
  11. Hamsa TP, Kuttan G (2012) Antiangiogenic activity of berberine is mediated through the downregulation of hypoxia-inducible factor-1, VEGF, and proinflammatory mediators. Drug ChemToxicol 35:57-70
  12. Hamsa TP, Kuttan G (2012) Berberine inhibits pulmonary metastasis through down-regulation of MMP in metastatic B16F-10 melanoma cells. Phytother Res 26:568-578
  13. Pratheeshkumar P, Kuttan G (2012) Modulation of cytotoxic T lymphocyte, natural killer cell, antibody-dependent cellular cytotoxicity, and antibody-dependent complement-mediated cytotoxicity by Vernoniacinerea L. and vernolide-A in BALB/c mice via enhanced production of cytokines IL-2 and IFN-gamma. ImmunopharmacolImmunotoxicol 34:46-55
  14. Siveen KS, Kuttan G (2012) Effect of Aervalanata on cell-mediated immune responses and cytotoxic T-lymphocyte generation in normal and tumor-bearing mice. J Immunotoxicol 9:25-33
  15. Siveen KS, Kuttan G (2012) Modulation of humoral immune responses and inhibition of proinflammatory cytokines and nitric oxide production by 10-methoxycanthin-6-one. ImmunopharmacolImmunotoxicol 34:116-125
  16. Hamsa T, Kuttan G (2011) Ipobscurine, an indole alkaloid from Ipomoea obscura, inhibits tumor cell invasion and experimental metastasis by inducing apoptosis. J Environ PatholToxicolOncol 30:163-178
  17. Hamsa T, Kuttan G (2011) Studies on anti-metastatic and anti-invasive effects of harmine using highly metastatic murine B16F-10 melanoma cells. J Environ PatholToxicolOncol 30:123-137
  18. Kuttan G, Pratheeshkumar P, Manu KA, Kuttan R (2011) Inhibition of tumor progression by naturally occurring terpenoids. Pharmaceutical biology 49:995-1007
  19. Pratheeshkumar P, Kuttan G (2011) Vernolide-A inhibits radiation-induced hypoxia-mediated tumor angiogenesis by regulating HIF-1alpha, MMP-2, MMP-9, and VEGF. J Environ PatholToxicolOncol 30:139-151
  20. Siveen KS, Kuttan G (2011) Effect of amentoflavone, a phenolic component from Biophytumsensitivum, on cell cycling and apoptosis of B16F-10 melanoma cells. J Environ PatholToxicolOncol 30:301-309
  21. Jeena K, Liju VB, Ramanath V, Kuttan R (2016) Protection against Whole Body gamma-Irradiation Induced Oxidative Stress and Clastogenic Damage in Mice by Ginger Essential Oil. Asian Pacific journal of cancer prevention : APJCP 17:1325-1332
  22. Pandaran Sudheeran S, Jacob D, Natinga Mulakal J, Gopinathan Nair G, Maliakel A, Maliakel B, Kuttan R, Im K (2016) Safety, Tolerance, and Enhanced Efficacy of a Bioavailable Formulation of Curcumin With Fenugreek Dietary Fiber on Occupational Stress: A Randomized, Double-Blind, Placebo-Controlled Pilot Study. J Clin Psychopharmacol 36:236-243
  23. Firdous AP, Kuttan G, Kuttan R (2015) Anti-inflammatory potential of carotenoid meso-zeaxanthin and its mode of action. Pharmaceutical biology 53:961-967
  24. Issac A, Gopakumar G, Kuttan R, Maliakel B, Krishnakumar IM (2015) Safety and anti-ulcerogenic activity of a novel polyphenol-rich extract of clove buds (Syzygium aromaticum L). Food Funct 6:842-852
  25. Kuttan R, Panikkar B, Binitha PP (2015) Amino acids in sandal (Santalum album L) with special reference to cis-4-hydroxy-l-proline and sym. homospermidine. Springerplus 4:015-1303
  26. Liju VB, Jeena K, Kuttan R (2015) Gastroprotective activity of essential oils from turmeric and ginger. J Basic Clin Physiol Pharmacol 26:95-103
  27. Liju VB, Jeena K, Kumar D, Maliakel B, Kuttan R, I MK (2015) Enhanced bioavailability and safety of curcumagalactomannosides as a dietary ingredient. Food Funct 6:276-286
  28. Im K, Issac A, Nm J, Ninan E, Maliakel B, Kuttan R (2014) Effects of the polyphenol content on the anti-diabetic activity of Cinnamomum zeylanicum extracts. Food Funct 5:2208-2220
  29. Jeena K, Liju VB, Viswanathan R, Kuttan R (2014) Antimutagenic potential and modulation of carcinogen-metabolizing enzymes by ginger essential oil. Phytother Res 28:849-855
  30. Liju VB, Jeena K, Kuttan R (2014) Chemopreventive activity of turmeric essential oil and possible mechanisms of action. Asian Pacific journal of cancer prevention : APJCP 15:6575-6580
  31. Firdous AP, Sindhu ER, Ramnath V, Kuttan R (2013) Amelioration of radiation-induced damages in mice by carotenoid meso-zeaxanthin. Int J Radiat Biol 89:171-181
  32. Firdous AP, Sindhu ER, Ramnath V, Kuttan R (2013) Anticarcinogenic activity of meso-zeaxanthin in rodents and its possible mechanism of action. Nutr Cancer 65:850-856
  33. Jeena K, Liju VB, Kuttan R (2013) Antioxidant, anti-inflammatory and antinociceptive activities of essential oil from ginger. Indian J Physiol Pharmacol 57:51-62
  34. Liju VB, Jeena K, Kuttan R (2013) Acute and subchronic toxicity as well as mutagenic evaluation of essential oil from turmeric (Curcuma longa L). Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 53:52-61
  35. Sindhu ER, Kuttan R (2013) Carotenoid lutein protects the kidney against cisplatin-induced acute renal failure. J Environ Pathol Toxicol Oncol 32:21-28
  36. Sindhu ER, Firdous AP, Ramnath V, Kuttan R (2013) Effect of carotenoid lutein on N-nitrosodiethylamine-induced hepatocellular carcinoma and its mechanism of action. Eur J Cancer Prev 22:320-327
  37. Sindhu ER, Firdous AP, Viswanathan R, Kuttan R (2012) Antimutagenic activity of Lutein--an oxycarotenoid present in the macula and its inhibition of cytochrome P 450 enzymes in vitro. Drug Metab Lett 6:213-220
  38. Firdous AP, Kuttan R (2012) Amelioration of cisplatin-induced toxicity in mice by carotenoid meso-zeaxanthin. Hum Exp Toxicol 31:710-717
  39. Firdous AP, Kuttan R (2012) Chemo protective activity of carotenoid meso-zeaxanthin against doxorubicin-induced cardio toxicity. J Exp Ther Oncol 10:101-106
  40. Sindhu ER, Kuttan R (2012) Carotenoid lutein protects rats from gastric ulcer induced by ethanol. J Basic Clin Physiol Pharmacol 23:33-37
  41. Divya M K, Salini S, Meera N, Lincy L, Seema M, A. C. Raghavamenon and Babu T D (2016). Attenuation of DMBA/croton oil induced mouse skin papilloma by Apodytes dimidiata mediated by its antioxidant and antimutagenic potential. Pharm Biol 15, 1-11.
  42. Divya M K, Lincy L, A. C. Raghavamenon and Babu T D (2016). Ameliorative effect of Apodytes dimidiata on cisplatin-induced nephrotoxicity in Wistar rats. Pharm Biol 3, 1-9 (ahead of print).
  43. Divya M K, Salini S, Chubicka T, Raghavamenon A C and Babu T D (2015). Evaluation of Cytotoxic and Antitumour Properties of Apodytes dimidiata and Characterisation of the Bioactive Component. Planta Med 81, 1705-1711.
  44. Salini S, Divya M K, Chubicka T, Meera N, Fulzele D P, A. C. Ragavamenon and Babu T D (2015). Protective effect of Scutellaria species on AAPH-induced oxidative damage in human erythrocyte. Journal of basic and clinical physiology and pharmacology (in press).
  45. A. P Shahid, S .Salini, N. Sasidharan, J. Padikkala, A. C Raghavamenon and T D Babu (2015). Effect of Saracaasoca (Asoka) on estradiol induced keratinizing metaplasia in rat uterus. Journal of Basic Clinical Physiology and Pharmacology 26:509-515.
  46. T. Chubicka, D. Girija, S. Salini S, A.C Raghavamenon and TD Babu (2014). Tumour inhibitory effect of a crystal protein from Bacillus thuringiensis isolate of Peninsular India. International Journal of Pharmaceutical Research. 7 (4).
  47. M.K Divya, D.Sheema, A. C. Raghavamenon and TD Babu (2014) Cytotoxic and antitumor effect of Tribulus terrestrisL frouit methanol extract. J Pharmacog and Phytochem 3 (2):1-4.
  48. J.M. Jeksy, P. Jayaram, T.D. Babu and A. C. Raghavamenon (2014) Antioxidant and anti-inflammatory properties of a nontoxic herbal formulation-GSTC. Int.J.phamtech Res. 6 924-932.
  49. Salini, T. Chubicka, A.C Raghavamenon, and T.D. Babu (2014) Evaluation of antioxidant Activities of Radermachera xylocarpa K.Schum. Int. J. pharmatech.Res.6 704-709.
  50. Salini S, Chubicka T, Sasidharan N, Sindhu E R and T D Babu (2013). Cytotoxic and antioxidant properties of selected Scutellaria species from the Western Ghats of Peninsular India. Pharmaceutical Biology 51(2), 152–159.
  51. Divya M K, Salini S, Meera N, Lincy L, Seema M, A. C. Raghavamenon and Babu T D (2016). Attenuation of DMBA/croton oil induced mouse skin papilloma by Apodytes dimidiata mediated by its antioxidant and antimutagenic potential. Pharm Biol 15, 1-11.
  52. Arunaksharan N, Reshma K. M., Shabna K. A., Smitha K. R., Indu M. S., Jeksy J. M., Balu T. K. and A. C. Raghavamenon (2016). Virgin coconut oil maintains redox status and improves glycemic conditions in high fructose fed rats. Journal of food science and technology, 53 (1): 895-901.
  53. Divya M K, Lincy L, A. C. Raghavamenon and Babu T D (2016). Ameliorative effect of Apodytes dimidiata on cisplatin-induced nephrotoxicity in Wistar rats. Pharm Biol 3, 1-9 (ahead of print).
  54. Jeksy Jos Manalil, Indu M. S., Smitha K. R., Arunaksharan N and A. C. Raghavamenon (2015). Component Authentication and Standardisation of an Anti-atherosclerotic Herbal Formulation-GSTC3. Pharmacognosy Journal, 7 (6): 339-343.
  55. Divya M K, Salini S, Chubicka T, Raghavamenon A C and Babu T D (2015). Evaluation of Cytotoxic and Antitumour Properties of Apodytes dimidiata and Characterisation of the Bioactive Component. Planta Med 81, 1705-1711.
  56. Salini S, Divya M K, Chubicka T, Meera N, Fulzele D P, A. C. Ragavamenon and Babu T D (2015). Protective effect of Scutellaria species on AAPH-induced oxidative damage in human erythrocyte. Journal of basic and clinical physiology and pharmacology (in press).
  57. Manalil J J, Baby M, Ramavarma S K, Suseela I M, Padikkala J and A.C. Raghavamenon (2015). Development of an Anti-Atherosclerotic Polyherbal Formulation: GSTC3. J Environ Pathol Toxicol Oncol 34, 237-248.
  58. P.S. Vipin, N.M. Johannah , M.Seema ,L. Lincy , A. C. Raghavamenon and J. Padikkala (2015) Enhancement of functional HDL contributing to anti-atheorogenic efficacy of Desmodium gyrans DC. WJPPS,4: 1631-1646
  59. S.S Nair, J.J Manalil, S.K Ramavarma, I.M Susheela, A. Thekkepatt and A.C Raghavamenon (2015) Virgin coconut oil supplementation ameliorates cyclophosphamideinduced systemic toxicity in mice. Human experimental toxicology, 35: 205-212.
  60. A. P Shahid, S .Salini, N. Sasidharan, J. Padikkala, A. C Raghavamenon and T D Babu (2015). Effect of Saracaasoca (Asoka) on estradiol induced keratinizing metaplasia in rat uterus. Journal of Basic Clinical Physiology and Pharmacology 26:509-515.
  61. T. Chubicka, D. Girija, S. Salini S, A.C Raghavamenon and TD Babu (2014). Tumour inhibitory effect of a crystal protein from Bacillus thuringiensis isolate of Peninsular India. International Journal of Pharmaceutical Research. 7 (4).
  62. M.K Divya, D.Sheema, A. C. Raghavamenon and TD Babu (2014) Cytotoxic and antitumor effect of Tribulus terrestrisL frouit methanol extract. J Pharmacog and Phytochem 3 (2):1-4
  63. J.M. Jeksy, P. Jayaram,T.D. Babu and Raghavamenon AC (2014) Antioxidant and anti-inflammatory properties of a nontoxic herbal formulation-GSTC. Int.J.phamtech Res. 6 924-932.
  64. S. Salini,T.Chubicka, A.C Raghavamenon, and T.D.Babu (2014) Evaluation of antioxidant Activities of Radermachera xylocarpa K.Schum. Int. J. pharmatech.Res.6 704-709.
  65. M. Faruq, A.C. Raghavamenon, M.O. Claville, Kumar C.SSR. Kumar and R.M. Uppu (2014) Targeted hyperthermia-induced cancer cell death by superparamagnetic iron oxide nonoparticles conjugated to luteinizing hormone-releasing hormone. NTREV. 3: 389-400.
  66. L. Laynes, A.C. Raghavamenon, O. D’Auvergne, V. Achuthan, and R.M. Uppu (2011). MAPK signaling in H9c2 cardiomyoblasts exposed to cholesterol secoaldehyde – Role of hydrogen peroxide. Biochem. Biophys. Res. Commun. 404, 90-95.
  67. A.C. Raghavamenon, A.F. Muyiwa, L.K. Davis, and R.M. Uppu (2011). Dihydroartemisinin induces caspase-8-dependent apoptosis in murine GT1-7 hypothalamic neurons. Toxicol. Mech. Methods. 23: 367-373..
  68. K. Sathishkumar, X. Gao, A.C. Raghavamenon, S.N. Murthy, P.J. Kadowitz, and R.M. Uppu (2010). Determination of Glutathione, Mitochondrial Transmembrane Potential, and Cytotoxicity in H9c2 Cardiomyoblasts Exposed to Reactive Oxygen and Nitrogen Species Methods Mol. Biol. 610, 51-61.
  69. K. Sathishkumar, A.C. Raghavamenon, K. Ganeshkumar, R. Telaprolu, N.L. Parinandi, and R.M. Uppu (2010). Simultaneous analysis of multiple redox-sensitive and apoptotic gene expression in hypothalamic neurons exposed to cholesterol ozonation products. Methods Mol. Biol. 610, 263-284.
  70. E. S. O’Connor Butler, J.N. Mazerik, J.P. Cruff, S.I. Sherwani, B.K. Weis, C.B. Marsh, A.C. Raghavamenon, R.M. Uppu, H.O. Schmid, and N.L. Parinandi (2010). Lipoxygenase-catalyzed phospholipid peroxidation: Preparation, purification, and characterization of phosphatidylinositol peroxides. Methods Mol. Biol. 610, 387-401.
  71. S .Parthasarathy, A.C Raghavamenon, M.O. Garelnabi, and N. Santanam (2010). Oxidized low density lipoprotein. Methods Mol. Biol. 610, 403-418
  72. A.C. Raghavamenon, R.Gernapudi, S.Babu, O.Auvergne, S.N. Murthy, P.J. Kadowitz, and R.M.Uppu (2009). Intracellular oxidative stress and cytotoxicity in rat primary cortical neurons exposed to cholesterol secoaldenyde. Biochem.Biophys. Res.Commun. 386, 170-174.
  73. A.C. Raghavamenon, M. Garelnabi, S. Babu, A.D. Litvinov, and S. Parthasarathy (2009). α-Tocopherol is ineffective in preventing the decomposition of pre-formed lipid peroxides and may promote the accumulation of toxic aldehydes: A potential explanation for the failure of antioxidants to affect human atherosclerosis. Antioxid. Redox Signal. 11, 1227-1235.
  74. X . Gao, A. C. Raghavamenon, O. D'Auvergne, and R.M. Uppu (2009). Cholesterol secoaldehyde induces apoptosis in J774 macrophages via mitochondrial pathway but not involving reactive oxygen species as mediators. Biochem. Biophys. Res. Commun. 389, 382-389.
  75. S. Babu, A.C. Raghavamenon, F.R. Fronczek, and R.M. Uppu (2009). 4-Hydroxy-3-methoxy-5-nitroacetophenone (5-nitroapocynin). Acta Cryst. E 65, 2292-2293 [suppl., pp. 1-10].
  76. A. C. Raghavamenon, C.J. Dupard, B. Kandlakunta, and R.M. Uppu (2009). Determination of alloxan by fluorometric, reversed-phase HPLC. Toxicol. Mech. Methods 19, 485-502.
  77. K. Sathishkumar, X. Gao, A.C. Ragavamenon, N.L. Parinandi, W.A. Pryor, and R.M. Uppu (2009). Cholesterol secoaldehyde induces apoptosis in cardiomyocytes through reactive oxygen species involving mitochondrial and death receptor pathways. Free Radic. Biol. Med. 47, 548-558.
  78. P.A. Nazeem, C.R. Achuthan,* T.D. Babu, G.V. Parab, D. Girija, R. Keshavachandran, and R. Samiyappan (2008). Expression of pathogenesis related proteins in black pepper (Piper nigrum L.) in relation to Phytophthora foot rot disease. J. Trop. Agri. 46, 33–39.
  79. P.A. Nazeem, R. Keshavachandran, T.D. Babu, C.R. Achuthan,* D. Girija, and K.V. Peter (2007). Assessment of genetic variability in black pepper (Piper nigrum L.) varieties through RAPD and AFLP analyses. Recent trends in Horticultural Biotechnology (R. Keshavachandran, Eds.), New India Publishing Agency, New Delhi, pp. 485-490.